2021/10/31
Generation of a Transgenic Zebrafish Line for In Vivo Assessment of Hepatic Apoptosis |
2021/08/19
Patient-Derived Cancer Xenograft Zebrafish Model (PDXZ) for Drug Discovery Screening and Personalized Medicine |
2021/07/09
Quality Control Protocol for Zebrafish Developmental Toxicity Studies |
2020/10/13
Gap junction protein beta 4 plays an important role in cardiac function in humans, rodents, and zebrafish |
2020/05/28
A novel orexin antagonist from a natural plant was discovered using zebrafish behavioural analysis |
2019/10/15
C3orf70 Is Involved in Neural and Neurobehavioral Development |
2019/09/22
Generation of a Triple-Transgenic Zebrafish Line for Assessment of Developmental Neurotoxicity during Neuronal Differentiation |
2019/07/17
Aging-associated microstructural deterioration of vertebra in zebrafish |
2019/03/18
Zebrafish yolk sac microinjection of thalidomide for assessment of developmental toxicology |
2019/02/18
Toxicological Evaluation of SiO2 Nanoparticles by Zebrafish Embryo Toxicity Test |
2018/12/27
Increased susceptibility to oxidative stress-induced toxicological evaluation by genetically modified nrf2a-deficient zebrafish. |
2018/01/18
EGF receptor kinase suppresses ciliogenesis through activation of USP8 deubiquitinase |
2017/11/23
Chemokines protect vascular smooth muscle cells from cell death induced by cyclic mechanical stretch. |
2017/07/29
New photic stimulating system with white light-emitting diodes to elicit electroretinograms from zebrafish larvae. |
2017/03/09
Potential protective function of the sterol regulatory element binding factor 1-fatty acid desaturase 12 axis in early-stage age-related macular degeneration |
2016/07/11
Activation of Sterol Regulatory Element Binding Factors by Fenofibrate and Gemfibrozil Stimulates Myelination in Zebrafish |
2016/06/14
Downregulation of GSTK1 Is a Common Mechanism Underlying Hypertrophic Cardiomyopathy |
2016/06/07
Comparative Transcriptome Analysis Identifies CCDC80 as a Novel Gene Associated with Pulmonary Arterial Hypertension |
2016/06/06
Establishment of a drug evaluation model against light-induced retinal degeneration using adult pigmented zebrafish |
2016/05/19
EP300 Protects from Light-Induced Retinopathy in Zebrafish |
2016/04/22
E2F4 Promotes Neuronal Regeneration and Functional Recovery after Spinal Cord Injury in Zebrafish |
2016/03/18
Comparative study of the zebrafish embryonic toxicity test and mouse embryonic stem cell test to screen developmental toxicity of human pharmaceutical drugs |
2016/03/14
DNA Damage Response Is Involved in the Developmental Toxicity of Mebendazole in Zebrafish Retina |
2016/01/11
Using zebrafish in systems toxicology for developmental toxicity testing. |
2015/12/18
Novel immunologic tolerance of human cancer cell xenotransplants in zebrafish. |
2015/12/08
In Vivo Detection of Mitochondrial Dysfunction Induced by Clinical Drugs and Disease-Associated Genes Using a Novel Dye ZMJ214 in Zebrafish |
2015/10/13
Pharmacological profiling of zebrafish behavior using chemical and genetic classification of sleep-wake modifiers |
2015/09/02
Systems pharmacology of adiposity reveals inhibition of EP300 as a common therapeutic mechanism of caloric restriction and resveratrol for obesity |
2015/05/20
E2F8 promotes hepatic steatosis through FABP3 expression in diet-induced obesity in zebrafish. |
2015/03/24
In vivo selective imaging and inhibition of leukemia stem-like cells using the fluorescent carbocyanine derivative, DiOC5(3) |
2015/03/01
Copper Oxide Nanoparticles Reduce Vasculogenesis in Transgenic Zebrafish Through Down-Regulation of Vascular Endothelial Growth Factor Expression and Induction of Apoptosis |
2014/11/04
In vivo imaging of the mouse neurovascular unit under chronic cerebral hypoperfusion. |
2014/11/03
Downregulation of Stanniocalcin 1 is Responsible for Sorafenib-Induced Cardiotoxicity |
2014/09/11
Zebrafish xenotransplantation model for cancer stem-like cell study and high-throughput screening of inhibitors |
2014/09/01
Zebrafish as a systems toxicology model for developmental neurotoxicity testing. |
2014/08/27
書籍「Cancer Cell Signaling」 |
2014/08/10
Zinc finger MYND-type containing 8 promotes tumour angiogenesis via induction of vascular endothelial growth factor-A expression |
2014/08/07
Effects of Yuzu (Citrus junos Siebold ex Tanaka) peel on the diet-induced obesity in a zebrafish model |
2014/01/15
Eriocitrin ameliorates diet-induced hepatic steatosis with activation of mitochondrial biogenesis |
2014/01/15
Quantitative Phenotyping-Based In Vivo Chemical Screening in a Zebrafish Model of Leukemia Stem Cell Xenotransplantation |
2013/11/20
Downregulation of max dimerization protein 3 is involved in decreased visceral adipose tissue by inhibiting adipocyte differentiation in zebrafish and mice. |
2013/07/15
S-nitrosylation regulates mitochondrial quality control via activation of parkin. |
2013/05/23
Identification of a Novel Indoline Derivative for in Vivo Fluorescent Imaging of Blood-Brain Barrier Disruption in Animal Models. |
2013/05/15
Fluorescent-Based Methods for Gene Knockdown and Functional Cardiac Imaging in Zebrafish. |
2013/05/13
A Novel, Reliable Method for Repeated Blood Collection from Aquarium Fish. |
2013/01/04
A High-Throughput Fluorescence-Based Assay System for Appetite-Regulating Gene and Drug Screening |
2012/08/20
SEMA4A mutations lead to susceptibility to light irradiation, oxidative stress, and ER stress in retinal pigment epithelial cells. |
2012/08/16
In vivo assessment of the permeability of the blood-brain barrier and blood-retinal barrier to fluorescent indoline derivatives in zebrafish |
2012/08/07
Green tea extract suppresses adiposity and affects the expression of lipid metabolism genes in diet-induced obese zebrafish |
2011/12/19
A Novel Protocol for the Oral Administration of Test Chemicals to Adult Zebrafish |
2011/12/13
Transcriptome analysis of anti-fatty liver action by Campari tomato using a zebrafish diet-induced obesity model. |
2011/05/11
DEVELOPMENT OF ZEBRAFISH-BASED ASSAYS FOR THE ASSESSMENT OF DNT CAUSED BY EXPOSURE TO CHEMICALS AT LOW DOSES |
2010/10/21
Diet-induced obesity in zebrafish shares common pathophysiological pathways with mammalian obesity |
2010/09/15
In vivo imaging of zebrafish retinal cells using fluorescent coumarin derivatives |
2010/01/01
CCDC132 is highly expressed in atopic dermatitis T cell |
2009/10/12
Synergistic induction of heme oxygenase-1 by nicaraven after subarachnoid hemorrhage to prevent delayed cerebral vasospasm. |
2009/06/18
Zebrafish beta-adrenergic receptor mRNA expression and control of pigmentation. |
2008/05/01
Pharmacogenomics of cardiovascular pharmacology: pharmacogenomic network of cardiovascular disease models. |
2008/02/29
Guinea pig cysteinyl leukotriene receptor 2 (gpCysLT2) mediates cell proliferation and intracellular calcium mobilization by LTC4 and LTD4. |
2007/01/01
Phosphodiesterase and Intracellular Signaling |
2006/12/08
Novel reciprocal regulation of cAMP signaling and apoptosis by orphan G-protein-coupled receptor GPRC5A gene expression. |
2005/01/01
Rapid and stable buffer exchange system using InSitu Chip suitable for multicolor and large-scale whole-mount analyses. |
2004/01/01
Changes in Cyclic Nucleotide Phosphodiesterase Activity and Calmodulin Concentration in Heart Muscle of Cardiomyopathic Hamsters. |
2004/01/01
Potential role for heat shock protein 72 in antagonizing cerebral vasospasm after rat subarachnoid hemorrhage. |
2003/01/01
Target validation in hypoxia-induced vascular remodeling using transcriptome/metabolome analysis. |
2002/01/01
Identification of highly expressed genes in peripheral blood T cells from patients with atopic dermatitis. |
2002/01/01
Cloning and characterization of the highly expressed ETEA gene from blood cells of atopic dermatitis patients. |
2002/01/01
Genomic organization,chromosomal localization,and alternative splicing of the human phosphodiesterase 8B gene. |
2001/01/01
Molecular Cloning of Novel Mouse and Human Putative Citrate Lyase. |
2001/01/01
Calcium-dependent Activation of NFIL3/E4BP4 Gene Expression by Calcineurin/NFAT and CaM kinase Signaling. |
2001/01/01
Loss of nuclear localization of the S100C protein in immortalized human fibroblasts. |
2001/01/01
The Functional Significance of Heme Oxygenase-1 Gene Induction in a Rat Vasospasm Model. |
2000/01/07
Ca2+-dependent Inhibition of Actin-activated Myosin Atpase Activity by S100C(S100A11), A Novel Member of the S100 Protein Family. |
2000/01/07
Phosphorylation sites by protein kinase C and functional domain of smooth muscle calponin. Kyoto Symposia on Bioscience, VII. |
2000/01/01
Automated DNA fragment collection by capillary array gel electrophoresis in search of differentially expressed genes. |
2000/01/01
Pharmacogenomics and therapeutic target validation in cerebral vasospasm. |
2000/01/01
Calcium-dependent Translocation of S100A11 Requires Tubulin Filaments. |
2000/01/01
Relationship between contact inhibition and intranuclear S100C of normal human fibroblasts. |
2000/01/01
Transcriptional and post-transcriptional regulation of monocyte chemoattractant protein-3 gene expression in human endothelial cells by phorbol ester and cAMP signalling. |
2000/01/01
Ca2+-dependent Inhibition of Actin-activated Myosin Atpase Activity by S100C(S100A11), A Novel Member of the S100 Protein Family. |
1999/01/01
Human S100A11 Exhibits Differential Steady-State RNA Levels in Various Tissues and Distinct Subcellular Localization. |
1999/01/01
Heme Oxygenase-1 Gene Induction as an Intrinsic Regulation against Delayed Cerebral Vasospasm in Rats. |
1999/01/01
Regulatory Mechanisms of Calponin Phosphorylation in Endothelin-1-induced Contraction of Porcine Coronary Artery. |
1999/01/01
Molecular Cloning and Characterization of Mammalian Homologues of Vesicle-Associated Membrane Protein-Associated (VAMP-Associated) Proteins. |
1998/12/13
Overexpression of caltractin gene in Tumor-Infiltrating Lymphocytes. |
1998/02/24
A Unique Exon-intron Organization of a Porcine S100C Gene: Close Evolutionary Relationship to Calmodulin Genes. |
1998/01/15
Two distinct actin-binding sites of smooth muscle calponin. |
1997/08/20
Propiverine Hydrochloride, Anti-Pollakiuric Agent, inhibits the Activity of Actomyosin ATPase from the Urinary Bladder. |
1997/01/13
QM Is a Novel Zinc-Binding Transcription Regulatory Protein : Its Binding to c-Jun Is Regulated by Zunc Ions and Phosphorylation by Protein Kinase C. |
1996/03/27
Novel Specific Chemotactic Receptor for S100L Protein on Guinea Pig Eosinophils. |
1995/09/01
A Calponin Peptide Enhances Ca2+ Sensivity of Smooth Muscle Contraction without Affecting Myosin Light Chain Phosphorylation |
1995/05/25
Protein Kinase C-Independent Activation of Raf-1 and Mitogen-Activated Protein Kinase by Leukotriene B4 in Guinea Pig Eosinophils |
1995/03/08
Phosphorylation of Calponin Mediated by Protein Kinase C in Association with Contraction in Porcine Coronary Artery |
1995/01/01
Inhibition by wortmannin of M-current in bullfrog sympathetic neurones |
1994/12/02
Characterization of the Myosin-binding Subunit of Smooth Muscle Myosin Phosphatase |
1994/09/29
Purification and characterization of a novel calcium-binding protein, S100C, from porcine heart |
1994/09/01
Identification and characterization of isoenzymes of cyclic nucleotide phosphodiesterase in human kidney and heart, and the effects of new cardiotonic agents on these isoenzymes. |
1994/02/01
Separation and characterization of a novel isoenzyme of cyclic nucleotide phosphodieterase from rat cerebrum. . |
1993/12/11
Myosin Light Chain Kinase Occurs in Bullfrog Sympathetic Neurons and May Modulate Voltage-Dependent Potassium Currents. |
1993/06/30
Calponin phosphatase from smooth muscle : A possible role of type 1 protein phosphatase in smooth muscle relaxation. |
1993/03/25
Identification of the regulatory site in smooth muscle calponin that is phosphorylated by protein kinase C. |
1993/01/29
Two isoforms of cGMP-inhibited cyclic nucleotide phosphodiesterases in human tissues distinguished by their responses to vesnarinone, a new cardiotonic agent. |
1992/12/07
Inhibition of actin-activated myosin Mg2+-ATPase in smooth muscle by ruthenium red. |
1992/10/25
Ruthenium red inhibits the binding of calcium to calmodulin required for enzyme activation |
1992/09/01
Cardiac sarcoplasmic reticulum chloride channels regulated by protein kinase A. |
1992/01/01
Cyclic AMP Phosphodiesterase from human heart and drug action. |
1991/12/16
Molecular cloning and expression of the cDNA coding for a new member of the S100 protein family from porcine cardiac muscle. |
1991/10/01
The catalytic subunit of cyclic AMP-dependent protein kinase directly inhibits sodium channel activities in guinea-pig ventricular myocytes. |
1990/09/28
Modulation of smooth muscle calponin by protein kinase C and calmodulin. |
1990/05/31
Effects of ruthenium red on activation of Ca2+-dependent cyclic nucleotide phosphodiesterase. |
1990/03/30
Phosphorylation of high-Mr caldesmon by protein kinase C modulates the regulatory function of this protein on the interaction between actin and myosin. |
1990/02/15
Effects of amrinone and enoximone on the subclasses of cyclic AMP phosphodiesterase from human heart and kideny. |
1989/11/15
Selective low level of protein kinase C isozyme in a tumor promoter-dependent mouse leukemia cell line. |
1989/07/01
Monoclonal antibody assessment of tissue- and species-specific myosin light chain kinase isozymes.. |
1989/01/01
S-100 antigen and calmodulin in human leukemic cells. |
1989/01/01
Molecular properties of calcium-binding proteins from bovine cardiac muscle. |
1989/01/01
Calcium signaling of calcium-binding proteins and drug actions. |
1988/09/01
Immunocytochemical evidence for translocation of protein kinase C in human megakaryoblastic leukemic cells : Synergistic effects of Ca2+ and activators of protein kinase C on the plasma membrane association. |
1988/08/01
Differential effects of flavonoids as inhibitors of tyrosine protein kinases and serine /threonine protein kinases. |
1988/07/01
Inhibition of human platelet secretion and of Ca2+, calmodulin-dependent protein phosphorylation by the antiallergic agent, GMCHA. |
1988/07/01
Putative binding site(s) of 1-(5-isoquinolinesulfonyl)-2-methylpiperazine (H-7) on protein kinase C. |
1988/05/15
Selective inhibition of cyclic AMP phosphodiesterase from various human tissues by milrinone, a potent cardiac bipyridine. |
1988/05/15
Selective inhibition of cyclic AMP phosphodiesterase from various human tissues by milrinone, a potent cardiac bipyridine. |
1988/05/05
Modulation of tyrosine phosphorylation of p36 and other substrates by the S-100 protein. |
1988/04/05
Cell type-specific expression of protein kinase C isozymes in the rabbit cerebellum. |
1988/02/01
Calmodulin-dependent calcium signal transduction. |
1988/01/01
Effects of cilostazol, a selective cAMP phosphodiesterase inhibitor on the contraction of vascular smooth muscle.. |
1988/01/01
Selective inhibitors of calmodulin-dependent phosphodiesterase and other enzymes. |
1988/01/01
Ca2+, phospholipid and Ca2+, calmodulin-dependent myosin light chain phosphorylation of smooth muscle and nonmuscle cells. |
1987/11/13
Different sensitivities of Ca2+, calmodulin-dependent cyclic nucleotide phosphodiesterases from rabbit aorta and brain to dihydropyridine calcium channel blockers. |
1987/07/01
Selective modulation of calcium-dependent myosin phosphorylation by novel protein kinase inhibitors, isoquinolinesulfonamide derivatives. |
1987/06/30
The Ca2+-activated protease (Calpain) modulates Ca2+/calmodulin dependent activity of smooth muscle myosin light chain kinase. |
1987/01/01
Isolation and structural analysis of the chromosomal gene for chicken calmodulin. |
1987/01/01
Transmembrane Ca2+ signaling and a new class of inhibitors. |
1986/11/28
N-(6-phenylhexyl)-5-chloro-1-naphthalenesulfonamide is one of a new class of activators for Ca2+-activated, phospholipid-dependent protein kinase. |
1986/11/01
Effect of calmodulin inhibitors on thyroid hormone secretion. |
1986/07/29
N-(6-phenylhexyl)-5-chloro-1-naphthalenesulfonamide, a novel activator of protein kinase C. |
1986/03/29
Modulation of calmodulin function and of Ca2+-induced smooth muscle contraction by the calmodulin antagonist, HT-74. |
1986/01/15
The binding of the calcium channel blocker, bepridil, to calmodulin. |
1985/09/10
Ca2+-dependent cyclic nucleotide phosphodiesterase is activated by poly(L-aspartic acid). |
1985/07/16
Calcium-dependent interactions of an ionophore A23187 with calmodulin. |
1984/11/01
Purification of cyclic adenosine monophosphate phosphodiesterase from human platelets using new-inhibitor Sepharose chromatography. |
1984/01/14
Calcium-dependent hydrophobic chromatography of calmodulin, S-100 protein and troponin-C. |
1983/03/01
Calcium-independent activation of calcium ion dependent cyclic nucleotide phosphodiesterase by synthetic compounds: quinazolinesulfonamide derivatives. |
1983/01/01
Calmodulin antagonists enhance calcium binding to calmodulin. |
1983/01/01
Naphthalenesulfonamides as calmodulin antagonists. |
1983/01/01
Calcium-dependent interactions with calmodulin of a fluorescent calmodulin antagonist: N2-dansyl-L-arginine-4-t-butylpiperidine amide. |
1982/09/22
Hydrophobic interaction of the Ca2+-calmodulin complex with calmodulin antagonists. Naphthalenesulfonamide derivatives. |
1982/09/22
Two types of calcium-dependent protein phosphorylations modulated by calmodulin antagonists. Naphthalenesulfonamide derivatives. |
1981/12/10
Calcium-dependent affinity chromatography of S-100 and calmodulin on calmodulin antagonist-coupled Sepharose. |
1981/11/20
Activity-structure relationship of calmodulin antagonists, Naphthalenesulfonamide derivatives. |
1981/07/30
Interaction of local anesthetics with calmodulin. |
1981/07/01
N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation. |
1981/04/30
Gonadotropin response to luteinizing hormone releasing hormone in hyperthyroid patients with menstrual disturbances. |
1981/01/01
Biopharmacological assessment of calmodulin function: utility of calmodulin antagonist naphthalenesulfonamide. |
1980/12/10
Hydrophobic regions function in calmodulin-enzyme(s) interactions. |
1980/10/30
Ca2+-calmodulin-dependent phosphorylation and platelet secretion. |
1980/08/27
Effect of beta-adrenergic blockade on plasma dopamine-beta-hydroxylase activity and triiodothyronine in hyperthyroidism. |
1980/01/17
Calcium-regulated modulator protein interacting agents inhibit smooth muscle calcium-stimulated protein kinase and ATPase. |
1980/01/15
Activation of myosin light chain kinase by trypsin. |