TOPICS
2025/05/02
新規蛍光色素ZMB741によるポドサイトパチー治療薬スクリーニング
2025/04/15
ポドサイトパチー創薬スクリーニング
2025/04/10
なぜ患者がん移植ゼブラフィッシュモデル(PDXZ)は、有効か
2025/02/01
Zebrafish-Based Oncocardionephrology
2025/01/01
２０２５年元旦謹賀新年
》oncocardiology of sorafenib
2023/04/28
Oncocardiology is a subspecialty of cardiology that focuses on the prevention, diagnosis and treatment of cardiovascular complications caused by cancer therapies. Sorafenib is a tyrosine kinase inhibitor that is used to treat advanced hepatocellular carcinoma and renal cell carcinoma. However, sorafenib can also induce cardiotoxicity, such as hypertension, left ventricular dysfunction, heart failure and ischemia. The characterization of oncocardiology of sorafenib involves the identification of risk factors, biomarkers and imaging modalities that can help to monitor and manage the cardiac effects of this drug. Additionally, the characterization of oncocardiology of sorafenib requires the development of strategies to prevent or mitigate cardiotoxicity, such as dose adjustment, drug interruption or discontinuation, and the use of cardioprotective agents.