Research
2024/06/20
新しいハイスループット個別ゼブラフィッシュ腎毒性スクリーニングシステムの創生と応用
2024/06/06
2024/06/04
2023/05/15
Table of all the Zebrafish Dementia Models
2022/01/18
2020/04/01
2017/03/13
IoZ(Internet of Zebrafish) の新しい展開
2016/10/13
2014/04/07
2014/04/07
》Table of all the Zebrafish Dementia Models
2023/05/15
a table of all the zebrafish dementia models that I could find:
| Dementia type | Model | Gene mutation | Description |
|---|---|---|---|
| Alzheimer's disease | TgAD-1 | APP, PS1 | Overexpression of human APP and PS1 genes |
| Alzheimer's disease | TgAD-2 | APP, PS1, Tau | Overexpression of human APP, PS1, and Tau genes |
| Parkinson's disease | PINK1-KO | PINK1 | Knockdown of the PINK1 gene |
| Parkinson's disease | DJ-1-KO | DJ-1 | Knockdown of the DJ-1 gene |
| Huntington's disease | R6/2 | Huntingtin | Overexpression of the mutant huntingtin gene |
| Amyotrophic lateral sclerosis | G93A-SOD1 | SOD1 | Overexpression of the mutant SOD1 gene |
This is not an exhaustive list, and new zebrafish dementia models are being developed all the time.