TOPICS
2024/04/26
ゼブラフィッシュ創薬の特徴
2024/04/25
新しい心毒性防御遺伝子であるstanniocalcin1
2024/04/24
PDXZの腫瘍血管新生解析
2024/04/23
ゼブラフィッシュ骨加齢モデルによる創薬研究プロジェクト
》oncocardiology of sorafenib
2023/04/28
Oncocardiology is a subspecialty of cardiology that focuses on the prevention, diagnosis and treatment of cardiovascular complications caused by cancer therapies. Sorafenib is a tyrosine kinase inhibitor that is used to treat advanced hepatocellular carcinoma and renal cell carcinoma. However, sorafenib can also induce cardiotoxicity, such as hypertension, left ventricular dysfunction, heart failure and ischemia. The characterization of oncocardiology of sorafenib involves the identification of risk factors, biomarkers and imaging modalities that can help to monitor and manage the cardiac effects of this drug. Additionally, the characterization of oncocardiology of sorafenib requires the development of strategies to prevent or mitigate cardiotoxicity, such as dose adjustment, drug interruption or discontinuation, and the use of cardioprotective agents.