2024/05/02
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2024/05/01
high-throughput individual zebrafish screening
2024/04/26
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2024/04/25
discovery of stanniocalcin1 as cardiotoxic defence gene
2024/04/24
Tumour Angiogenesis in Patient-Deriveved Xenograft Zebarafish Model
BioJapan2021: Oct 13-15, 2021
We developed novel zebrafish model for patient-derived xenograft (PDXZ), and demonstrated that PDXZ has high rate and speed of engraftment in normal zebrafish when the immune system is immature, requires less than 100 cancer cells for transplantation, and can be quantitatively analyzed in 2 days. We report on drug efficacy screening system that can be quantitatively analyzed within a week.
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Patient-Derived Cancer Xenograft Zebrafish Model (PDXZ) for Quantitative Drug Discovery Screening